Modification of amyloid-beta peptide aggregation via photoactivation of strained Ru(ii) polypyridyl complexes
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چکیده
منابع مشابه
Oxidative modification of glutamine synthetase by amyloid beta peptide.
beta-Amyloid peptide (A beta), the main constituent of senile plaques and diffuse amyloid deposits in Alzheimer's diseased brain, was shown to initiate the development of oxidative stress in neuronal cell cultures. Toxic lots of A beta form free radical species in aqueous solution. It was proposed that A beta-derived free radicals can directly damage cell proteins via oxidative modification. Re...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2021
ISSN: 2041-6520,2041-6539
DOI: 10.1039/d1sc00004g